Omeprazole Capsule 20mg
Each capsule contains omeprazole 20 mg
Orally administered omeprazole is well absorbed but to a variable
extent. Absorption of omeprazole takes place in the small intestine
and is usually completed within three to six hours. Bioavailability
depends on dose and gastric pH and may reach 70% with repeated
administration. Food has no influence on the bioavailability of
Omeprazole is more than 95% bound to plasma proteins. Clearance
from the circulation is by hepatic metabolism with a plasma
half-life of 30 to 90 minutes.
|•||Treatment of duodenal ulcer, including prevention of relapse
gastric ulcer and reflux oesophagitis.|
|•||Long-term management of reflux oesophagitis and Zollinger-Ellison
|•||Symptomatic relief of heartburn in patients with gastro-oesophageal
reflux disease and the short-term relief of functional dyspepsia.|
|•||Helicobacter pylori-positive duodenal ulcers as part of an
eradication programme with appropriate antibiotics.|
|•||Treatment of non-steroidal anti-inflammatory drugs -associated
gastric and/or duodenal ulcer/erosions.|
|•||Reduction of the risk to develop gastric and/or duodenal
ulcer/erosions and reduction of the risk of relapse for previously
healed gastric and/or duodenal ulcer/erosions in patients on NSAID
|Short-term (up to 3 months) treatment of severe ulcerative reflux
oesophagitis resistant to previous medical treatment.|
Hypersensitivity to any of the ingredientsDosage:
Safety in pregnancy and lactation has not been established.
One capsule a day or as directed by the physician.
Omeprazole competes with other drugs for the subfamily 2C of the
cytochrome P450 system. This reduces the rate of metabolism of
diazepam, phenytoin and warfarin resulting in an increase in the
plasma drug level.
Diarrhoea, skin rashes and headache are reported frequently. Other
adverse effects reported rarely include myalgia, blood disorders
including leucopenia and thrombocytopenia.
Important: Do not chew or crush the capsules. They should be
swallowed whole with water.
Store in a cool, dry place, Protect from light.