Each 2ml ampoule contains cyanocobalamin (Vitamin B12) USP 1000mcg
or 2000mcg. Vitamin BI2 Injection is a sterile solution of
Cyanocobalamin in water for Injections containing. This agent is
pinkish to red supernatant light
Vilamin B12 water -solution vitamin, occurs in the body mainly as
methyleohydroxocobabmin (TnecobailEimm) and as adenosylcobalamin
(eobamamide) and hydroxocobalamin. Mecobalamin and eobamamide act
as coenzymes in nucleic acid synthesis. Mecobalamin is also closcly
involved with folic acid in several important metabotic pathways.
Vitamin B12 plays an important role in the formation of red blood
cells, for neurological health and the production of DNA. B12
injections are available with a doctor's prescription and indicated
for people who cannot maintain diet-bound blood serum levels of
B12. Foods rich in B12 include beef liver, clams and fortified
cereal and milk. Anemia, fatigue, weakness, weight loss and loss of
appetite are a few of the symptoms of a B12 deficiency.
Vitamin B12 has extremely low toxicity, and even taking enormous
doses does not appear to be harmful to healthy individuals.
Peripheral vascular thrombosis has been reported. Treatment of
vitamin B12 deficiency can unmask polycythemia vera, which is
characterized by an increase in blood volume and the number of red
blood cells. The correction of megaloblastic anemia with vitamin
B12 can result in fatal hypokalemia and gout in susceptible
individuals, and it can obscure folate deficiency in megaloblastic
Leber's disease: Vitamin B12 in the form of cyanocobalamin is
contraindicated in early Leber's disease, which is hereditary optic
nerve atrophy. Cyanocobalamin can cause severe and swift optic
atrophy, but other forms of vitamin B12 are available. However, the
sources of this statement are not clear, while an opposing view
concludes: "The clinical picture of optic neuropathy associated
with vitamin B12 deficiency shows similarity to that of Leber's
disease optic neuropathy. Both involve the nerve fibers of the
papillomacular bundle. The present case reports suggest that optic
neuropathy in patients carrying a primary LHON mtDNA mutation may
be precipitated by vitamin B12 deficiency. Therefore, known
carriers should take care to have an adequate dietary intake of
vitamin B12 and malabsorption syndromes like those occurring in
familial pernicious anaemia or after gastric surgery should be
Precautions & Warning:
Before using cyanocobalamin, tell your doctor or pharmacist if you
are allergic to it; or to cobalt; or if you have any other
allergies. Your doctor may recommend that you receive a smaller
test dose before starting your regular dose. This product may
contain inactive ingredients, which can cause allergic reactions or
other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your
medical history, especially of: low potassium blood levels
(hypokalemia), gout, a certain blood disorder (polycythemia vera),
a certain eye disease (Leber's disease), other vitamin/mineral
deficiencies (especially folic acid and iron).
This product may contain aluminum, which can infrequently build up
to dangerous levels in the body. The risk may be increased if this
product is used for an extended time, especially in newborns or in
people with kidney disease. Tell your doctor immediately if you
notice any symptoms of too much aluminum in the body such as muscle
weakness, bone pain, or mental changes.
Store below 25℃ in well- closed containers. Protect from light.
Keep out of reach of children.